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Publication Icon   Literature - Publication Review
HTRF and AlphaLISA assays bring clarity to extracellular matrix related fibrosis development
This note gathers publications that exemplify various applications of HTRF™ and AlphaLISA™ assays to advance fibrosis related research and shows how other researchers have harnessed these technologies to move their studies forward.
Guide Icon   Guide
User’s guide: Alpha protein:protein interaction assays
Explore AlphaScreen™ and AlphaLISA™ assays—where proximity meets luminescence. Discover protein interactions in a microplate format.
Brochure Icon   Brochure
chemagic brochure
This brochure gives overview about all automated RNA/DNA extraction workflows with the chemagic instruments.
Guide Icon   Guide
LANCE Ultra cAMP Assay development guidelines
The LANCE™ Ultra cAMP Assay Development Guidelines offer detailed instructions for accurately measuring cyclic adenosine monophosphate (cAMP) levels in cell lysates and membrane samples.
Technical Note Icon   Technical Note
Optimized EnVision Nexus Alpha performance using apertures and crosstalk minimization mode
Explore AlphaLISA™ and AlphaScreen™ technologies for protein analysis. Learn how EnVision Nexus™ enhances Alpha detection with improved crosstalk reduction and flexibility compared to EnVision™ 2105.
Technical Note Icon   Technical Note
A simple method for preparing GPCR membrane model extracts from stable cell lines for use with the HTRF GTP Gi binding assay
This Technical Note provides a detailed method for preparing GPCR membrane model extracts from stable cell lines for use with the HTRF GTP Gi binding assay, including cell culture preparation, cell lysis, membrane extraction, and assay optimization.
Application Note Icon   Application Note
Characterizing Chemokine Receptor Inhibitors with AlphaLISA SureFire Ultra
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases.
Guide Icon   Guide
Improving immunotherapy by targeting the tumor stroma
Utilize this guide for detailed scientific information on the tumor stroma and tools to further your immunotherapy research.
Application Note Icon   Application Note
A fast and simple chemiluminescent assay for monitoring of DNA-protein interactions
In this application note, we use HepG2 nuclear extracts to demonstrate the binding of Sp1 and HNF1 transcription factors to tagged oligonucleotides containing required cognate response elements. Read this note to see the results and access detailed data compared to EMSA.
Technical Note Icon   Technical Note
PROTAC degraders targeting CDK4/CDK6 for the study of cell cycle regulation in oncology
Explore the cell cycle with AlphaLISA™ SureFire® Ultra™ and investigate Cyclin D1 and key proteins' roles in cancer prognosis, PROTAC, and NRG1 treatments.
Guide Icon   Guide
Understanding obesity: exploring cellular pathways and mechanisms
Several cellular pathways can become deregulated and contribute to the development and progression of obesity. Learn more about the main cellular mechanisms involved in obesity in this guide.
Flyer Icon   Flyer
No-wash cytokine assay solutions
Learn about our full range of no-wash cytokine assays, enabling your research and ability to easily detect and quantify cytokines.
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