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Application Note Icon   Application Note
Avoiding biotin interference in AlphaLISA assays
This application note demonstrates the value of using AlphaLISA biotin-free kits to reduce the effects of biotin interference in sample and standard preparations.
Whitepaper Icon   Whitepaper
Alpha technologies for antibody detection and characterization
Alpha technology is homogeneous and non-radiometric with distinct features that makes it enabling in comparison to other proximity assays.
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DELFIA Assays: Flexible and Sensitive Tools for Monoclonal Antibody Development
DELFIA assay design is very flexible, enabling effective screening in cases where either purified antigen or polyclonal antibodies are in limited supply. The wide dynamic range of DELFIA immunoassays also make them ideal for post-screening applications
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Comparison of EMT Biomarker Expression in 2D Monolayer and 3D Spheroid Cultures in a Prostate Cancer
This application note shows that AlphaLISA can be used to compare differences in protein expression levels and cellular tolerance for compound treatment between a human prostate cancer cell line grown in monolayers and those same cells grown in 3D spheroids.
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LANCE Ultra TR-FRET-based detection and modulation of phosphorylated STAT3 levels in human cells.
STAT3 is a particularly important therapeutic target since it is constitutively active in a range of cancer cells lines and human tumors. Therefore, fast and easy methods for screening of inhibitors of STAT3 activation are highly desirable.
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Simultaneous Detection of IL-6 and IL-8 Secretion by Cell Lines using AlphaPlex Technology
This application note describes how AlphaPlex reagents from Revvity can be used to simultaneously detect IL-6 and IL-8 secretion by cell lines.
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Excellent sensitivity from the EnVision Nexus multimode plate reader for AlphaLISA detection
This application note demonstrates the AlphaLISA detection capabilities of the EnVision Nexus and compares it to the EnVision 2105.
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Detection of MAPK activation to evaluate the efficacy and potency of KRAS/SOS1 inhibitors by AlphaLISA and HTRF technologies
Detection of MAPK activation to evaluate the efficacy and potency of KRAS/SOS1 inhibitors by AlphaLISA and HTRF technologies
Guide Icon   Guide
The ultimate guide to successful kinase binding experiments
This manual provides the kinase research community with the most up to date guidelines for the optimization of kinase assays.
Whitepaper Icon   Whitepaper
KRAS biomarker becomes a target of choice in certain cancer therapies
Get the latest insights on KRAS and see how it has switched from being an undruggable to a druggable cancer target
Guide Icon   Guide
Get your guide on fibrosis
A comprehensive overview of fibrosis development
Brochure Icon   Brochure
Detecting cytokines with AlphaLISA guide
Learn how to get the most out of your homogenous AlphaLISA cytokines assays with this comprehensive guide.
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