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The recent success of cell and gene therapies has paved the way for the next generation of advanced therapeutics. While challenges remain, cell and gene therapy research is seeing a transformational shift in the way that novel modalities, such as CAR-T, CRISPR, and vectors, are developed and delivered.
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The process of drug development comprises all the activities involved in bringing a new drug to market once a lead compound has been identified.
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Identify and characterize drug discovery targets with functional genomic screening services. Offering CRISPR knockout, CRISPR activation, CRISPR inhibition, dual screening and RNAi technologies
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Countless diseases, especially cancer, are highly heterogenous in nature which means a one-drug-fitsall approach isn’t practical for treating or fighting these diseases effectively.
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With decades of experience in drug discovery driven by strong customer relationships, Revvity has developed an excellent product portfolio of drug discovery tools for complete solutions serving all parts of the discovery workflow.
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Base editing with nuclease flexibility
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
Increasing the targeting scope and precision of next-generation gene editing technology
Base editing and stem-cell based therapies
Interchanging Cas enzymes, deaminases, and aptamerguide RNA combinations to achieve optimal editing with the modular Pin-point™ base editing platform
One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Addressing the challenges in solid tumor therapy with base editing
A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
CRISPR-derived base editing technology: The what, the how, and the why
The future of immunotherapy gets brighter with base editing
The Pin-point™ platform: A novel modular base editing system
A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout
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