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Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics
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Application of gene editing technologies to improve biotherapeutic manufacturing
Showcasing a multiplex gene editing approach with well-defined workflows and established tools to isolate, identify, and characterize edited knock-out or knock-in clones in different cell types.
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Efficient multiplexed targeted gene editing as a strategy to generate improved CHO host cell lines for biotherapeutic manufacturing applications
Learn about Revvity’s capabilities to simultaneous edit genes using CRISPR-Cas9 that incorporates stringent genetic QC steps for comprehensive characterization.
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One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.
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ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.
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Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.
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A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.
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Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
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Advancing Gene Editing Efficiency and Precision with the Pin-point™ Base Editing Platform
This webinar discusses how the Pin-point™ base editing platform can achieve more efficient and precise complex multiplex edits of cell lines, while decreasing the potential of unintended consequences.
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CHOSOURCE™ GS KO cell line: optimization, improvement strategy, and case study
On-demand webinar showing how to enhance bioprocess in CHO cell lines through molecular design, screening, and process optimization strategies, utilizing the CHOSOURCE expression platform.
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Redefining biotherapeutics and cell and gene therapies with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic
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CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.
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