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ValiScreen Human Serotonin 5-HT1A Cell Line, CHO-K1 Cells

Stable, recombinant ValiScreen® cell line expressing the Serotonin receptor 5-HT1A, human recombinant in CHO-K1 host cells.

For research use only. Not for use in diagnostic procedures. Cell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use. Click here.

Overview

Revvity's ValiScreen cell lines are provided in two vials of frozen cells, each containing ~2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line.

Clonal selection Revvity's ValiScreen cell lines is carried out with receptor binding. High and low expressors are n tested and selected optimal binding and functional response according to receptor specific transduction pathway.

Revvity’s ValiScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Please use link above to accept Terms and Conditions or to request an agreement for commercial use.

Specifications

Application
Drug Discovery & Development
Assay Validation
Binding
cAMP
GTPγS
Assay Target Class
GPCR
Assay Target Type
Cell line
Brand
ValiScreen
G-Alpha Natural Receptor
Gi/Go
Host
CHO-K1
One Unit Contains
2.0 Vials
Receptor Type
5-Hydroxytryptamine (Serotonin)
Second Messenger Release
GTP exchange
Species
Human
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
Requires accepted Terms and Conditions. Additional agreement needed for commercial use.
Therapeutic Area
Cardiovascular
Central Nervous System
Gastrointestinal
Inflammation
Metabolic
Unit Size
5 million cells

Resources

1-2 of 2 Resources
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Application Note
Measuring Performance of an Automated and Miniaturized LANCE Ultra cAMP Assay for the Gi-coupled 5-HT1A Receptor- a Comparative Study

In this note we describe the miniaturization of a LANCE Ultra cAMP assay from 384-to 1,536-well plate format for the...

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Brochure
Radioligand selection guide

Discover a comprehensive collection of GPCR cell lines, membrane preparations, and complementary radioligands designed to drive...

SDS, COAs, Manuals and more Illuminator

SDS, COAs, Manuals and more

Are you looking for technical documents for this product. We have housed them in a dedicated section., click on the links below to explore.

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