This Eu-cryptate conjugate allows specific detection of the K9Me0 motif on histone H3, as a result of demethylation or deacetylation enzymatic activity.
For research use only. Not for use in diagnostic procedures.
Feature | Specification |
---|---|
Application | Biochemical Enzymatic Assay |
This Eu-cryptate conjugate allows specific detection of the K9Me0 motif on histone H3, as a result of demethylation or deacetylation enzymatic activity.
For research use only. Not for use in diagnostic procedures.
Revvity offers a line of ready to use HTRF toolbox reagents for the construction of Histone H3 methyltransferase (HMT), demethylase (HDM) and deacetylase (HDAC) activity assays. This monoclonal antibody Eu-cryptate conjugate is specific for the histone H3K9Me0 methylation mark. It can be used for the development of biochemical assays with the highest levels of specificity and sensitivity, for the screening and study of both DMTs such as JMJD1A, and HDACs 1, 3-8, as well as SIRT1-3 and 6.
Application |
Biochemical Enzymatic Assay
|
---|---|
Brand |
HTRF
|
Detection Modality |
HTRF
|
Molecular Modification |
Methylation
|
Product Group |
Fluorescent Reagent
|
Shipping Conditions |
Shipped in Dry Ice
|
Target Class |
Epigenetics
|
Technology |
TR-FRET
|
Therapeutic Area |
Metabolism/Diabetes
Neuroscience
Oncology & Inflammation
|
Unit Size |
500 Assay Points
|
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