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HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
This immune checkpoint assay is designed to identify human LAG3/MHC II checkpoint inhibitors.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Protein-Protein Interaction |
| Sample Volume | 2 µL |
This immune checkpoint assay is designed to identify human LAG3/MHC II checkpoint inhibitors.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
Product information
Overview
The lymphocyte activation gene-3 (LAG-3), selectively transcribed in human activated T and NK cells, encodes a ligand for major histocompatibility complex (MHC) class II molecules. When LAG3 is bound to MHC II, T cell response is suppressed. Checkpoint inhibitors blocking LAG3/MHC II complex formation are generating considerable interest in cancer immunotherapy.
Specifications
| Application |
Protein-Protein Interaction
|
|---|---|
| Brand |
HTRF
|
| Detection Modality |
HTRF
|
| Product Group |
Kit
|
| Sample Volume |
2 µL
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Target Class |
Binding Assay
|
| Target Species |
Human
|
| Technology |
TR-FRET
|
| Therapeutic Area |
Oncology & Inflammation
|
| Unit Size |
10,000 Assay Points
|
Video gallery
HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
HTRF Human LAG3 / MHCII Binding Kit, 10,000 Assay Points
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This guide provides you an overview of HTRF applications in several therapeutic areas.
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