A cell-permeable activator of adenylyl cyclase to be used in the cAMP Gs and cAMP Gi kits
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Second Messenger Detection |
A cell-permeable activator of adenylyl cyclase to be used in the cAMP Gs and cAMP Gi kits
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Forskolin activates the adenylyl cyclase enzyme and increases the intracellular level of cAMP. It is used as a positive control for Gs applications ( biological models validation, maximal intracellular cAMP modulation determination). It is highly used for Gi coupled receptor study as a pre-activation step to reveal a cAMP inhibition upon cell stimulation.
Application |
Second Messenger Detection
|
---|---|
Brand |
HTRF
|
Detection Modality |
HTRF
|
Product Group |
Buffer
|
Shipping Conditions |
Shipped Ambient
|
Target Class |
GPCR
|
Technology |
TR-FRET
|
Therapeutic Area |
Cardiovascular
Infectious Diseases
Metabolism/Diabetes
NASH/Fibrosis
Neuroscience
Oncology & Inflammation
Rare Diseases
|
Unit Size |
40 Assay Points
|
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