The AlphaLISA™ SureFire® Ultra™ Human and Mouse Phospho-ß-Catenin (Thr41/Ser45) assay is a sandwich immunoassay for quantitative detection of phospho-ß-Catenin (Thr41/Ser45) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Catenin beta-1 (β-catenin) is a protein that is coded by the CTNNB1 gene. The Wnt/β-Catenin signaling pathway is crucial to regulating cell proliferation and polarity, cell determination, and tissue homeostasis. In the absence of extracellular WNT ligands, cytosolic β-Catenin is phosphorylated, thereby targeting the protein for ubiquitination, degradation, and inactivation. β-Catenin is implicated in various cancers and neurological diseases, such as salivary gland tumors, oral squamous cell carcinomas, Alzheimer’s disease, and Parkinson’s disease.
The AlphaLISA SureFire Ultra Human and Mouse Phospho-ß-Catenin (Thr41/Ser45) assay is a sandwich immunoassay for the quantitative detection of phospho-ß-catenin (Thr41/Ser45) in cellular lysates, using Alpha Technology.
Application |
Protein Analysis & Detection
Protein Detection
|
---|---|
Assay Target |
ß-Catenin
|
Assay Target Class |
Phospho-protein
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Central Nervous System
Oncology
|
Unit Size |
500 Assay Points
|
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