Solutions for key biomarker types
Explore our comprehensive solutions for key biomarker types, designed to transform your biomarker discovery and unlock new insights into disease mechanisms.
DNA and RNA biomarkers
DNA and RNA are powerful biomarkers in research and diagnostics, from gene expression and molecular signatures through treatment prognosis.
DNA and RNA are powerful biomarkers in research and diagnostics, from gene expression and molecular signatures through treatment prognosis.
Revvity offers comprehensive solutions for DNA and RNA (coding and non-coding) biomarker discovery, from sample preparation to large-scale automation. These tools facilitate efficient isolation, amplification, and analysis of nucleic acid biomarkers for precision medicine and drug development - supporting applications such as next-generation sequencing, including single-cell sequencing and targeted sequencing. Additionally, our solutions support the analysis of ctDNA, cfDNA, miRNA, and cfRNA.
Soluble or secreted protein biomarkers
Soluble proteins, such as cytoplasmic proteins and enzymes, and secreted proteins, such as cytokines or antibodies, play important roles in metabolism, signaling, and immune defense.
Soluble proteins, such as cytoplasmic proteins and enzymes, and secreted proteins, such as cytokines or antibodies, play important roles in metabolism, signaling, and immune defense.
Revvity provides sample homogenizers, microplate readers, immunoassay kits, and reagents for single and multiplex detection of numerous proteins. Choose from different technology platforms depending on your study question, sensitivity, dynamic range and throughput needs.
Single plex protein detection:
Multiplex protein detection:
Quantify up to 14 cytokines or analytes with our bead-based multiplex immunoassays on your flow cytometer.
Instruments:
Workflow automation:
Cell surface protein biomarkers
Detection of cell surface proteins is crucial to identify cell types and understand their various cellular functions.
Detection of cell surface proteins is crucial to identify cell types and understand their various cellular functions.
Flow cytometry is essential for cell surface protein analysis, providing rapid, multi-parameter data at the single-cell level. Enhance your flow cytometry analysis with BioLegend antibodies.
Utilize surface proteins to isolate and purify cells of interest for downstream analysis. Our magnetic bead-based cell separation system uses antibodies for either positive or negative selection of cells from heterogenous samples.
A crucial step in flow cytometry is the accurate preparation of reagents. Our liquid handling solutions enhance your productivity and support reliable antibody panel preparation.
Using flow cytometry and our lyophilized antibody arrays, you can screen hundreds of cell surface markers on mouse or human cells and determine your target cell antigen profile.
Immune cell profiling is a popular application within surface protein analysis. TotalSeq™ Phenocyte is a streamlined instrument-free workflow to identify, quantify and analyze different types of immune cells. Using a sequencing readout removes the spectral limitations of fluorescence-based flow cytometry.
Multiomic analysis integrates various levels of molecular information for deeper biological insights. Our TotalSeq reagents enable simultaneous detection of proteins and RNA or DNA in single-cell sequencing experiments, enhancing multiomic research capabilities.
Tissue biomarkers
Tissue-specific biomarkers that contribute to the organization and heterogeneity of tissues offer deeper insights into disease mechanisms and precision medicine.
Tissue-specific biomarkers that contribute to the organization and heterogeneity of tissues offer deeper insights into disease mechanisms and precision medicine.
By combining the high-resolution molecular profiling of single-cell sequencing with the spatial context provided by spatial biology techniques, researchers can gain a holistic understanding of tissue organization to fuel biomarker discovery.
Our antibody solutions add protein data to either single cell or spatial transcriptomics and enable multiplexed sequential/cyclical immunofluorescence applications.
Spatial transcriptomics
Immunofluorescence
Multiplexed/sequential immunofluorescence
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