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Molecular Detection of Y Mirodeletion AZFa, AZFb, AZFc
| Test Code | MDY002 |
|---|---|
| Test Summary | Qualitative Detection of Microdeletions in the Y-chromosomal regions AZFa, AZFb and AZFc (Y-Microdeletion - YCM) |
| Turn Around Time | 36 days |
| Acceptable Sample Types | Whole Blood (EDTA) |
| NY Approved | No |
| Accreditations | CAP , ISO 15189 (NABL) |
*TAT starts after the sample and all required sample information is received at the processing laboratory.
**The CPT codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association, and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party.
This testing service has not been cleared or approved by the U.S. Food and Drug Administration. Testing services may not be licensed in accordance with the laws in all countries. The availability of specific test offerings is dependent upon laboratory location.
**The CPT codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association, and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party.
This testing service has not been cleared or approved by the U.S. Food and Drug Administration. Testing services may not be licensed in accordance with the laws in all countries. The availability of specific test offerings is dependent upon laboratory location.
Revvity Sites Globally
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Test Code:
MDY002
Test Description
Y chromosome microdeletions are typically characterized by azoospermia, severe to moderate oligospermia, or abnormal sperm morphology/motility in men with a normal physical evaluation. Assisted reproductive techniques are contraindicated for men carrying AZFa, AZFb, AZFbc or AZFabc microdeletions, which are classically associated with spermatogenic failure.
Indications for Testing
Use to determine the cause of infertility in men with nonobstructive azoospermia or moderate or severe oligospermiaAids in predicting effectiveness of assisted reproductive technologies in men with specific Y chromosome microdeletions
Condition Description
PCR amplification of sequence-tagged-sites (STS) in the three regions of Y chromosome.
Test Methods and Limitations
PCR amplification of sequence-tagged-sites (STS) in the three regions of Y chromosome.
Detailed Sample Requirements
Whole Blood (EDTA)
| Collection Container(s) | EDTA (purple top) |
|---|---|
| Collection | Infants (< 2-years): 2 to 3 mL; Children (>2-years): 3 to 5 mL; Older children and adults: Minimum 5mL. The blood tube should be inverted several times immediately after blood collection to prevent coagulation. |
| Sample Condition | Store at ambient temperature. Do not refrigerate or freeze. |
| Shipping | Ship overnight at ambient temperature ensuring receipt within 5-days of collection. |
| Special Sample Instructions | Clotted or hemolyzed samples are not accepted. |