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FISH for Chromosome 18
| Test Code | FVB005 |
|---|---|
| Test Summary | Fluorescence in situ hybridization (FISH) is performed for aneuploidy detection of chromosome 18 |
| Turn Around Time | 3 days |
| Acceptable Sample Types | Whole Blood (EDTA) |
| NY Approved | No |
| Accreditations | CAP , ISO 15189 (NABL) |
*TAT starts after the sample and all required sample information is received at the processing laboratory.
**The CPT codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association, and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party.
This testing service has not been cleared or approved by the U.S. Food and Drug Administration. Testing services may not be licensed in accordance with the laws in all countries. The availability of specific test offerings is dependent upon laboratory location.
**The CPT codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association, and are provided for informational purposes only. CPT coding is the sole responsibility of the billing party.
This testing service has not been cleared or approved by the U.S. Food and Drug Administration. Testing services may not be licensed in accordance with the laws in all countries. The availability of specific test offerings is dependent upon laboratory location.
This test is not available in your region United States, please select your nearest laboratory to request more information.
Revvity Sites Globally
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Test Code:
FVB005
Test Description
FISH - Rapid detection of aneuploidy involving chromosome 18. Assay offered in conjunction with chromosome study.
Indications for Testing
FISH - The FISH analysis does not detect structural chromosome abnormalities, mosaicism, and other numerical chromosome abnormalities (excluding 13, 18, and 21). The American College of Medical Genetics recommends that irreversible therapeutic action should not be initiated on the basis of FISH results alone.
Condition Description
FISH
- Screening result suggests aneuploidy
- Advanced maternal age
- One major or at least two minor fetal structural defects found on ultrasound
- Previous fetus or child with aneuploidy
- Parent of this pregnancy has a structural chromosome abnormality (e.g.,translocation, inversion) involving chromosome 18
Test Methods and Limitations
FISH - Fluorescence in situ hybridization (FISH) Fluorescence Microscopy
Detailed Sample Requirements
Whole Blood (EDTA)
| Collection Container(s) | EDTA (purple top) |
|---|---|
| Collection | Infants (< 2-years): 2 to 3 mL; Children (>2-years): 3 to 5 mL; Older children and adults: Minimum 5mL. The blood tube should be inverted several times immediately after blood collection to prevent coagulation. |
| Sample Condition | Store at ambient temperature. Do not refrigerate or freeze. |
| Shipping | Ship overnight at ambient temperature ensuring receipt within 5-days of collection. |
| Special Sample Instructions | Clotted or hemolyzed samples are not accepted. |