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Article
Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
Whitepaper
Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.
Infographic
Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Whitepaper
AAV vectors: Pursuing a one-time therapy for ocular diseases
Explore the latest advancements in gene therapy and its transformative impact on ocular health.
Whitepaper
Innovative approaches for advancing genetic payload development
Discover the future of gene therapy in our white paper 'Innovative approaches for advancing genetic payload development.' Learn about the challenges and breakthroughs in gene editing, offering a glimpse into the evolving landscape of genetic medicine.
Whitepaper
The evolving landscape of quality by design in biologics manufacturing
Implement QbD principles to meet safety, efficacy, and consistency challenges in biologics manufacturing
Infographic
Solutions for virology research
Virology research solutions to enable virus monitoring, neutralization testing, as well as viral pathogenesis studies.
Whitepaper
Leveraging the microbiome to strengthen immune therapeutic response
Understanding the role bacteria play, whether it be oncogenesis, tumor promotion, or treatment effectiveness, may provide an opportunity for intervention at the microbiome level in favor of cancer regression.
Whitepaper
Spotlight research interview: narcolepsy, a neurological autoimmune disorder
Researchers were first to demonstrate direct evidence of autoreactive immune cells in narcolepsy patients, providing evidence of autoimmune basis
Literature - Publication Review
Prolonging ß cell proliferation with a 3D culture system
Disque Platform technology for evaluating drug candidates to treat ß cell loss in patients with diabetes.
Whitepaper
An emerging therapeutic modality - RNA carves its path out of the paradigm
Learn more about several promising classes of RNA therapeutic, including RNAi, CRISPR, base editing, and mRNA vaccines, as well as the potential to combine RNA technologies with CAR-T.
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