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Whitepaper
Get our White Paper about autoimmunity
A complete review on current and emerging therapeutic approaches for autoimmune diseases
Whitepaper
Download our white paper on the Human Kinome
Learn about cutting edge kinase research in this free white paper
Guide
Improving immunotherapy by targeting the tumor stroma
Utilize this guide for detailed scientific information on the tumor stroma and tools to further your immunotherapy research.
Infographic
Cell cycle infographic
Targeting various steps of the cell cycle is a promising strategy for cancer therapeutics. Learn more from our infographic.
Application Note
Quantifying the degradation of RBM39 in Neuroblastoma cells treated with molecular glue degraders using HTRF technology
This application note highlights the use of HTRF immunoassays to evaluate RBM39 degradation in neuroblastoma cancer cells treated with Indilsulam and CeMM1-4 molecular glue degraders.
Literature - Publication Review
Research and characterization of bispecific antibodies for cancer immunotherapies
In this literature review, we describe several functional approaches to characterize novel BsAbs targeting immune checkpoints and the tumor necrosis factor (TNF) superfamily, with easy-to-use immunoassays.
Whitepaper
Chimeric Antigen Receptor (CAR) Natural Killer cells: a promising cell therapy strategy for cancer treatment
Featured in this white paper is information on NK cells and cytotoxicity, CAR NK cell therapy description, including genetic modification and CAR generation, and advantages, limitations, and clinical progress of CAR NK cell therapy.
Infographic
Protein recycling, TPD, and neurodegenerative disease
Targeted protein degradation (TPD) via the proteasomal and lysosomal pathways is a promising therapeutic approach that represents a novel tool for exploring cellular pathways. TPD offers several key advantages over traditional occupancy-based inhibitors, notably concerning dosing, drug resistance, and side effects.
Application Note
Investigate mechanism of action of drugs targeting TDP-43 phosphorylation and aggregation with HTRF-based detection assays
This Application Note Illustrates how to assess phospho-TDP-43 modulation (Ser 409/410) with HTRF assays combined to the Protein Disaggregation kit in aggregated models.
Application Note
CDK signaling in oncology: evaluate phosphorylation events trigged by DNA damage
Learn how to evaluate DNA damage induced by etoposide and its impact on cyclin-dependent kinase (CDK1) signaling.
Technical Note
Key success tips to perform β-arrestin 2 recruitment assays by using the B-arr2 recruitment kit with GPCRs
This technical note provides valuable tips for performing B-arr2 recruitment assays on adherent cell lines overexpressing GPCRs.
Guide
The Gene Therapy Industry: A Brief Report
Gene therapy industry report: A growing market, current challenges, and an exciting future.
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