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Literature - Publication Review
The modulatory effects of A2AR on NMDAR functionality using primary neurons and microglia cultures for potential neuroprotection in Alzheimer’s disease
Neurodegenerative Diseases Therapies; CNS Research, A2AR, Alzheimer's Disease, NMDAR, Acetylcholinesterase inhibitors
Application Note
Measuring FRET using the Opera™ Phenix™ high-content screening system
Here, we present a FRET-based high-content screening assay to study the interaction of the anti-apoptotic protein Bcl-XL with the pro-apoptotic protein Bad.
Application Note
Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
Whitepaper
Targeting leishmaniasis with an entamoeba molecule
An immune-therapeutic approach to leishmaniasis treatment by targeting leishmaniasis with an entamoeba molecule.
Whitepaper
Assessing juvenile batten disease on Brain Development in In Vitro 3D organoid models
Assessing Juvenile Neuronal ceroid lipofuscinosis (JNCL) on brain development in Vitro 3D organoid Models.
Whitepaper
High-Throughput Approaches to Overcome Antimicrobial Resistance - Part 2
The use of machine learning algorithms to predict how an organism is going to behave in response to an antimicrobial.
Technical Note
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Technical Note
Quantitative analysis of lysine 36 demethylation with AlphaLISA
This technical note provides details on how the AlphaLISA immunodetection assay quantifies the demethylation of a biotinylated Histone H3 (21-44) peptide that is tri-methylated at lysine 36
Technical Note
AlphaLISA assays for immune checkpoint detection and quantitation
This Technical Note will provide you with guidelines on the quantification of immune checkpoints with AlphaLISA Biomarker Detection Kits.
Literature - Publication Review
Inhibiting interleukin 11 signaling reduces and reverses many dangerous effects of NAFLD/NASH in mouse models
Study demonstrating that inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of NASH
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