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Whitepaper
Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.
Whitepaper
Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.
Whitepaper
Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.
Scientific Poster
A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.
Webinar
wbs-strategies-for-therapeutic-screening-in-immune-cells
This on-demand webinar provides an overview into how integrating immune cell screening into drug discovery pipelines can provide insight into the immunogenicity of individuals and help to quickly characterize them.
Application Note
Rapid screening of novel therapeutics by ImmuSignature™ T cell activation assay
This application note describes the development of a robust T cell activation assay to assess the impact of novel therapeutics on T cell function.
Scientific Poster
Interchanging Cas enzymes, deaminases, and aptamerguide RNA combinations to achieve optimal editing with the modular Pin-point™ base editing platform
Learn how to apply multiplex base editing to efficiently develop engineered CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Base editing with nuclease flexibility
In this application note, we demonstrate how the Pin-point™ base editing platform’s modularity allows for its components to be optimized to the target site.
Literature - Publication Review
Empowering T cell therapies: the strategic use of LentiBOOST in CAR T and TCR modalities
This literature review demonstrates how the LentiBOOST™ transduction enhancer can be applied to CAR T and TCR modalities.
Application Note
Profiling compound effect on immune cells by combining ImmuSignature assays and LEGENDplex bead-based multiplex protein quantification
Explore Revvity's preclinical services for cell engineering and screening in our ebook.
Scientific Poster
One-step engineering of allogeneic cell therapies with Pin-point base editing platform and an AI-engineered Cas enzyme
This scientific poster describes a one-step process to engineer allogeneic cell therapies with the Pin-point base editing platform and an AI-engineered Cas enzyme.
Scientific Poster
A versatile base editing technology with broad Cas enzyme and deaminase compatibility well suited for Cell and Gene Therapy
This scientific poster describes the development of a versatile base editing platform for cell and gene therapy.
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