Resource Center
Explore Resource Types
We have housed the technical documents (SDS, COAs, Manuals and more) in a dedicated section.
Explore all All Resources
Filters
Select resource types (1)
Select products & services
Select solutions
Active Filters (1)
Clear All
13 - 24 of 425 Results
Sort by:
Best Match
Application Note
HTRF probes all types of protein-protein interaction
HTRF probes all types of protein-protein interaction, from small to very large complexes
Application Note
Inhibition of FGFR signaling pathways studied in cancer cell lines using HTRF
In this application note, we show that a pan-FGFR inhibitor, AZD4547, used in different clinical phases depending on the cancer type, is able to inhibit or even suppress the abnormal phosphorylation of FGFRs and their key effectors in 3 different types of cancer cell lines: KG-1 (blood cancer), SNU-16 (gastric cancer), and KMS-11 (multiple myeloma).
Application Note
HTRF assays handle low- to high affinity protein-protein interactions
This application note demonstrated that HTRF PPI reagents are successfully used combining high detection performance, accurate modulators screening, and pharmacological characterization.
Application Note
Kinetic Binding of Kinase inhibitors and determination of Kon, Koff rates
This application note presents the use of fluorescent kinase inhibitors to determine the kinetic binding properties of inhibitors of interest and demonstrates the pharmacological relevance of the kinase binding platform for both equilibrium-and kinetic profiling.
Application Note
Characterizing pharmacological compounds with complementary Upstream and Downstream GPCR readouts
This application note presents and compares the pharmacological characterization of a panel of reference compounds (full agonists, partial agonists, antagonists) in δ-opioid and D2 receptor models with two different Gi-coupled receptor activity monitoring assays: the HTRF® GTP Gi binding assay and the HTRF cAMP Gi assay.
Application Note
Research on neutralizing antibodies in autoimmune diseases
The data presented here demonstrates that HTRF biochemical and cellular assays offer a comprehensive and easy-to-implement platform for the identification of potent biotherapeutics to address autoimmune pathologies.
Application Note
Neuroinflammation study using TREM2 and SYK signaling pathways in human iPSC-derived microglia-like cells
This application note demonstrates the power of HTRF for TREM2 and SYK signaling in human iPSC-Derived macrophages studies.
Application Note
Unlock your STING polymorphism research with a comprehensive HTRF binding platform
This application note demonstrates how the HTRF STING binding assay platform represents a powerful new tool to identify and characterize compounds which bind to the STING protein
Application Note
Pharmacological validation of a panel of GPCRs with the HTRF GTP Gi Binding Assay
This application note discusses the characterization process for candidate molecules targeting Gα-protein activation through GPCRs with the functional HTRF GTP binding assay.
Application Note
Got Kinase Targets? KinEASE is here to help
This application note provides you the five steps required for a typical development for an HTRF KinEASE assay.
Application Note
A simple, reliable, no-wash assay platform for AAV capsid titer quantification based on HTRF technology
In this application note you will discover a reliable and efficient method for quantifying AAV titers for AAV1, AAV2, AAV3B, AAV5, AAV6, AAV8, and AAV9 serotypes.
Application Note
Adaptation of a bacterial growth detection assay on the VICTOR Nivo for measurement of antibiotic effects
In this application note, the VICTOR Nivo™ plate reader is used for automated detection of bacterial growth assay to help prevent common issues and to greatly reduce consumables and waste. Learn more.
Looking for technical documents?
Find the technical documents you need, ASAP, in our easy-to-search library.