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Application Note
CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation
This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.
Application Note
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening
Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.
Application Note
CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference
This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.
Flyer
Preclinical services reading list
Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Whitepaper
The importance of combination therapy for modern cancer treatments
This white paper discusses the importance of combination therapy for modern cancer treatments.
Whitepaper
How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.
Application Note
Induced regulatory T cell suppression assay for compound screening
This application note describes our high-throughput functional assay to assess the effect of compounds on iTreg function to enhance or inhibit their suppressive activity on T cells.
Application Note
Polarization of naïve CD4+ T cells to induced regulatory T cells for compound screening
This application note describes our screening platform for compound testing with the phenotypic characterization of iTregs.
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