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Vasopressin, [125I]Tyr2, Arg8-, 50µCi (1.85MBq)

Vasopressin, labeled with 125I on tyrosine residue 2. Vasopressin binds and activates vasopressin receptors, a group of GPCRs that are potential drug targets for hyponatremia, congestive heart failure, and cirrhosis.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Fresh Lot Days Second Monday of each month
Label Position Nominally Labeled
Molecular Weight ~ 1208
Receptor Vasopressin

Vasopressin, labeled with 125I on tyrosine residue 2. Vasopressin binds and activates vasopressin receptors, a group of GPCRs that are potential drug targets for hyponatremia, congestive heart failure, and cirrhosis.

For research use only. Not for use in diagnostic procedures.

Product Variants
Unit Size: 10 µCi
Part #:
NEX128010UC
List Price
USD 1,640.00
Unit Size: 50 µCi
Part #:
NEX128050UC
List Price
USD 3,862.00

Overview

50 µCi Quantities of Vasopressin, [125I]Tyr2, Arg8-, are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX128:

  1. Thiesson, H.C., Skøtt, O., Jespersen B., Schaffalitzky de Muckadell, O.B. (2003), Nitric Oxide Synthase Inhibition Does Not Improve Renal Function in Cirrhotic Patients With Ascites, American Journal of Gastroenterology 98, 180–186.
  2. Lishajko F, Appelgren B, Eriksson S. (1981) Cerebral sodium/angiotensin interaction studied by RIA-determination of urinary arginine vasopressin in the hydrated goat. Acta Physiol Scand. 111(3):311-8.

Specifications

Molecular Weight
~ 1208
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Lyophilized
Detection Modality
Radiometric
Fresh Lot Days
Second Monday of each month
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Vasopressin
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Therapeutic Area
CNS & Neurologic
Metabolic Disorders
Unit Size
50 µCi

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