U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
For research use only. Not for use in diagnostic procedures
U-69,593 acts as an agonist at kappa 1 opioid receptors (KORs). These receptors are a class of GPCRs involved in pain, consciousness, stress, and mood.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET952:
Molecular Weight |
356.5
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Application |
Drug Discovery & Development
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Brand |
NEN Radiochemicals
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Detection Method |
Radiometric
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Label Position |
Specifically Labeled
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One Unit Contains |
250.0 µCi
|
Radionuclide |
3H
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Radioisotope |
H-3
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Receptor Type |
Opioid
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Shipping Conditions |
Shipped in Dry Ice
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Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
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Therapeutic Area |
CNS & Neurologic
Inflammation
Pain
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Unit Size |
250 µCi
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