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Membrane Target Systems: Somatostatin sst2a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target Systems: Somatostatin SST2a (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

For research use only. Not for use in diagnostic procedures.

Feature Specification
µg protein/unit 25 µg protein / unit
Concentration 10 µg/µL protein
G-Alpha Natural Receptor Gi/Go, Gq/G11
Host Cell Line CHO-K1
Host Species Human
Receptor Somatostatin
Second Messenger Release GTP exchange
Target Class GPCR
Validation Binding
GTPγS
Volume 1000.0 µL

Our Membrane Target Systems: Somatostatin SST2a (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

For research use only. Not for use in diagnostic procedures.

Product Variant
Unit Size: 400 units
Part #:
ES-521-M400UA
List Price
USD 1,915.00

Overview

Membrane Target Systems are quality assured frozen membranes from cells that express Somatostatin SST2a (human) recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods). Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined bycompetition binding assay (filtration). A complete product description and recommended protocol are included on the Certificate of Analysis.

Some of our receptors may be restricted for sale in specifiedcountries. Please inquire.

Specifications

Concentration
10 µg/µL protein
Volume
1000.0 µL
µg protein/unit
25 µg protein / unit
Application
Drug Discovery & Development
Brand
Membrane Target Systems
Buffer/Solvent
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
G-Alpha Natural Receptor
Gi/Go, Gq/G11
Host Cell Line
CHO-K1
Host Species
Human
Product Group
Membrane Preparation
Receptor
Somatostatin
Second Messenger Release
GTP exchange
Shipping Conditions
Shipped in Dry Ice
Target Class
GPCR
Therapeutic Area
Central Nervous System
Gastrointestinal
Metabolic
Unit Size
400 units
Validation
Binding
GTPγS

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