Skip to main content
Menu
US

RTI-55, [125I]-, 250µCi (9.25MBq)

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Fresh Lot Days Fourth Monday of even months
Label Position Nominally Labeled
Molecular Weight 385.2
Receptor Dopamine

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Unit Size: 25 µCi
Part #:
NEX272025UC
List Price
USD 1,625.00
Unit Size: 250 µCi
Part #:
NEX272250UC
List Price
USD 5,715.00

Overview

250 µCi Quantities of RTI-55, [125I]- are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX272:

  1. Hong, W.C., Amara, S.G. (2010), Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem, 285 (42): 32616-32626.

Specifications

Molecular Weight
385.2
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Ethanol : water : acetonitrile (1:1:0.1)
Detection Modality
Radiometric
Fresh Lot Days
Fourth Monday of even months
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Dopamine
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
4°C
Therapeutic Area
CNS & Neurologic
Unit Size
250 µCi

Resources

Are you looking for resources, click on the resource type to explore further.

1-1 of 1 Resources
Guide Icon
Guide
Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...

Scroll Icon