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Membrane Target Systems: Prostanoid CRTH2 (human) membrane preparation, in CHO-K1 cells. 400 Units.
Membrane Target Systems: Prostanoid CRTH2 (human) membrane preparation, in CHO-K1 cells. 400 Units.
Receptor cell membranes
| Feature | Specification |
|---|---|
| µg protein/unit | 5 µg protein / unit |
| Concentration | 5 µg/µL protein |
| G-Alpha Natural Receptor | Gi |
| Host Cell Line | CHO-K1 |
| Host Species | Human |
| Receptor | Prostanoid |
| Second Messenger Release | GTP exchange |
| Target Class | GPCR |
| Validation |
Binding GTPγS |
| Volume | 400.0 µL |
Product variant
Unit Size: 400 units
Part #:
ES-561-M400UA
List price
USD 1,332.90
Your online price:
For research use only. Not for use in diagnostic procedures.
Membrane Target Systems: Prostanoid CRTH2 (human) membrane preparation, in CHO-K1 cells. 400 Units.
Receptor cell membranes
Membrane Target Systems: Prostanoid CRTH2 (human) membrane preparation, in CHO-K1 cells. 400 Units.
Product information
Overview
Membrane Target Systems are quality assured frozen membranes from cells that express Prostanoid CRTH2 (human) recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods). Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined bycompetition binding assay (filtration). A complete product description and recommended protocol are included on the Certificate of Analysis.
Some of our receptors may be restricted for sale in specifiedcountries. Please inquire.
Specifications
| Concentration |
5 µg/µL protein
|
|---|---|
| Volume |
400.0 µL
|
| µg protein/unit |
5 µg protein / unit
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
Membrane Target Systems
|
| Buffer/Solvent |
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
|
| G-Alpha Natural Receptor |
Gi
|
| Host Cell Line |
CHO-K1
|
| Host Species |
Human
|
| Product Group |
Membrane Preparation
|
| Receptor |
Prostanoid
|
| Second Messenger Release |
GTP exchange
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Target Class |
GPCR
|
| Therapeutic Area |
Immune
Inflammation
|
| Unit Size |
400 units
|
| Validation |
Binding
GTPγS
|
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