3-O-methyl-D-glucose, labeled on the methyl group with C-14. 3-O-methyl-D-glucose (OMG) is a glucose analog that is readily transported into most cells, but does not become phosphorylated and therefore will equilibrate across the cell membrane. Equilibrium is usually reached rapidly, so glucose uptake assays may only be linear for a short period of time; you may need to take your measurements fairly quickly. This analog cannot be further metabolized by cells.
For research use only. Not for use in diagnostic procedures.
Feature | Specification |
---|---|
Concentration | 0.1 mCi/ml |
Label Position | Specifically Labeled |
Molecular Weight | 194.2 |
3-O-methyl-D-glucose, labeled on the methyl group with C-14. 3-O-methyl-D-glucose (OMG) is a glucose analog that is readily transported into most cells, but does not become phosphorylated and therefore will equilibrate across the cell membrane. Equilibrium is usually reached rapidly, so glucose uptake assays may only be linear for a short period of time; you may need to take your measurements fairly quickly. This analog cannot be further metabolized by cells.
250 µCi quantities of 3-0-[Methyl-14C]-Methyl-D-glucose are available for your research. Application of [14C]3-O-Methyl-D-glucose ([14C]3OMG) can be found in: perfusion-independent effect of bradykinin and fosinoprilate on glucose transport in Langendorff rat hearts, phosphorylation of 3-O-methyl-D-glucose by yeast and beef hexokinase, prostanoid modulation of glucose transport in isolated diabetic rat uterus, effect of bioflavonoids on vincristine transport across blood–brain barrier, insulin down-regulating the Na+/K+ ATPase in enterocytes but increasing intestinal glucose absorption, etc.
Concentration |
0.1 mCi/ml
|
---|---|
Molecular Weight |
194.2
|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Buffer/Solvent |
Ethanol : water, (9:1)
|
Detection Modality |
Radiometric
|
Label Position |
Specifically Labeled
|
Packaging |
NENSure vial
|
Radioisotope |
14C
|
Shipping Conditions |
Shipped Ambient
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Storage Conditions |
-20°C
|
Unit Size |
250 µCi
|
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