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ValiScreen Human Melanocortin MC4 Cell Line, CHO-K1 Cells

Stable, recombinant ValiScreen® cell line expressing the Melanocortin MC4 receptor, human recombinant in CHO-K1 host cells.

For research use only. Not for use in diagnostic procedures. Cell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use. Click here.

Overview

Revvity's ValiScreen cell lines are provided in two vials of frozen cells, each containing ~2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line.

Clonal selection Revvity's ValiScreen cell lines is carried out with receptor binding. High and low expressors are n tested and selected optimal binding and functional response according to receptor specific transduction pathway.

Revvity’s ValiScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Please use link above to accept Terms and Conditions or to request an agreement for commercial use.

Specifications

Application
cAMP
Drug Discovery & Development
Assay Validation
Binding
cAMP
Assay Target Class
GPCR
Assay Target Type
Cell line
Brand
ValiScreen
G-Alpha Natural Receptor
Gs
Host
CHO-K1
One Unit Contains
2.0 Vials
Receptor Type
Melanocortin
Second Messenger Release
cAMP
Species
Human
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
Requires accepted Terms and Conditions. Additional agreement needed for commercial use.
Therapeutic Area
Central Nervous System
Inflammation
Metabolic
Pain
Unit Size
5 million cells

Resources

1-2 of 2 Resources
Application Note Icon
Application Note
cAMP AlphaScreen assay: a method for the pharmacological characterization and screening of Gαi coupled receptors in whole cells

G protein-coupled receptors (GPCRs) are a large family of transmembrane receptors that are significant drug targets. They function...

Application Note Icon
Application Note
cAMP Assay Provides Flexibility and Stable Pharmacology

GPCR activity for the subunits Gαs and Gαi is commonly assessed by measuring levels of intracellular cAMP upon stimulation by...

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