IVISense Tumor Metabolism Fluorescent Imaging Panel

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IVISense Tumor Metabolism Fluorescent Imaging Panel

Advance your understanding of cancer using IVISense^™ Tumor Metabolism Fluorescent Imaging Panel specific for measuring and detecting tumor metabolism in vivo.

For research use only. Not for use in diagnostic procedures.

Product information

SDS, COAs, Manuals and more

Product information

Overview

Tumors modify the cellular metabolism in cancer cells when compared to normal healthy cells. They alter pathways of nutrient acquisition and metabolism to meet increased energy, synthetic, and proliferative demands. Biomarkers of tumor metabolism offer not only opportunities to study tumor progression but also to specifically assess therapies that target critical pathways in tumor metabolism. Our fluorescent imaging probes provide a variety of tools for quantifying key receptors associated with proliferation and nutrient uptake as well as biomarkers of cell death, protease activity, and vascular leak.

The availability of probes at 680 nm and 750 nm wavelengths further offer the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.

Additional product information

Our IVISense tumor metaolism fluorescent imaging panel includes the following seven probes

Part number	Fluorescent probe	Biological target
NEV10054EX	IVISense Vascular 680 (AngioSense 680EX)	Vascular probe: Leaks into sites of edema
NEV10168	IVISense MMP 750 FAST (MMPSense 750 FAST)	Pan-MMP activatable probe: Secreted marker of neutrophils, macrophages, and mast cells
NEV10003	IVISense Pan Cathepsin 680 (ProSense 680)	Pan-cathepsin activatable probe: Lysosomal marker of a variety of inflammatory cells
NEV10040	IVISense Folate Receptor 680 (FolateRSense 680)	Folate receptor targeted probe: Marker on inflammatory cells; metabolic marker on tumor cells
NEV10090	IVISense Bombesin Receptor 680 (BombesinRSense 680)	Bombesin receptor targeted probe: Metabolic marker on tumor cells
NEV10091	IVISense Transferrin Receptor 750 (Transferrin-Vivo 750)	Transferrin receptor targeted probe: Iron metabolism marker on tumor cells
NEV11053	IVISense Annexin-V 750 Fluorescent Probe (Annexin-Vivo)	Death/apoptosis probe: Detects surface phosphatidylserine increase on dying cells

Specifications

Other Specifications

Brand	IVISense
Imaging Modality	Fluorescence
Optical Imaging Classification	Fluorescence Imaging
Quantity in a Package Amount	7.0 Vials
Shipping Conditions	Shipped in Blue Ice
Therapeutic Area	Tumor Metabolism
Unit Size	1 kit containing 7 vials