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IVISense Renin 680 FAST Fluorscent Probe (ReninSense)
IVISense™ Renin 680 FAST (ReninSense™) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.
For research use only. Not for use in diagnostic procedures.
Product information
Overview
IVISense Renin 680 FAST™ is a member of a family of activatable fluorescent imaging probes comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.
IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.
Specifications
| Brand |
IVISense
|
|---|---|
| Fluorescent Agent Type |
Activatable
|
| Optical Imaging Classification |
Fluorescence Imaging
|
| Quantity in a Package Amount |
1.0 Units
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Unit Size |
1 Vial (10 doses)
|
| Wave Length |
680 nm
|
Resources
The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...
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