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IVISense Pan Cathepsin 750 FAST Fluorescent Probe (ProSense)

Name: IVISense Pan Cathepsin 750 FAST Fluorescent Probe (ProSense)
Price: 676.29 USD
Availability: InStock

Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

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Feature	Specification
Unit Size	1 vial (10 doses)
Specificity	Cathepsin proteases

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Product variants

Wave Length: 680 nm

Part #:

NEV10003

List price

USD 581.26

Your online price:

Wave Length: 750 nm

Part #:

NEV10001EX

List price

USD 612.39

Your online price:

Wave Length: 750 nm

Style

FAST

Part #:

NEV11171

List price

USD 676.29

Your online price:

For research use only. Not for use in diagnostic procedures.

Total list price:

USD 676.29

Product information

Overview

IVISense Pan Cathepsin 750 FAST is a member of a family of activatable fluorescent imaging agents comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology) that confers an improved pharmacokinetic profile with a broader range of early imaging time points. This architecture also offers higher target specific signal with reduced background. IVISense Pan Cathepsin 750 FAST offers faster activation after injection; it can be imaged at earlier times for optimized work flow, or for applications such as acute inflammation models. 4-24h imaging at 750 nm.

Specifications

Other specifications

Brand	IVISense
Fluorescent Agent Type	Enzyme activated
Imaging Modality	Fluorescence
Shipping Conditions	Shipped in Blue Ice
Specificity	Cathepsin proteases
Storage Conditions	+2 to +8 °C
Style	FAST
Therapeutic Area	Arthritis Atherosclerosis Inflammation Oncology Pulmonary Vascular
Unit Size	1 vial (10 doses)
Wave Length	750 nm