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IVISense Osteo 800 Fluorescent Probe (OsteoSense)
Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISense™ Osteo Fluorescent Imaging probes (OsteoSense™). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.
IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.
For research use only. Not for use in diagnostic procedures.
For research use only. Not for use in diagnostic procedures.
Product information
Overview
IVISense Osteo NIR fluorescent bisphosphonate imaging probes are designed to bind with high affinity to hydroxyapatite (HA) both in vivo and in vitro. Since HA is known to bind pyrophosphonates and phosphonates as well as synthetic bisphosphonates with high affinity, IVISense Osteo agents offer a safe and easy means to assess the subtle bone mineral changes that occur in bone growth, bone loss, and in diseases that damage bone, using subtherapeutic doses for imaging.
IVISense Osteo 800 is excited by 780 ± 10 mn excitation light and emits at 805 ± 10 mn. Including IVISense Osteo 800 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.
Specifications
| Brand |
IVISense
|
|---|---|
| Fluorescent Agent Type |
Targeted
|
| Optical Imaging Classification |
Fluorescence Imaging
|
| Quantity in a Package Amount |
1.0 Units
|
| Shipping Conditions |
Shipped Ambient
|
| Therapeutic Area |
Arthritis
Atherosclerosis
Oncology/Cancer
|
| Unit Size |
1 Vial (10 doses)
|
| Wave Length |
800 nm
|
Resources
Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...
Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...
The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...
Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...
IVISense Osteo fluorescent agents optimized and validated hydroxyapatite-targeting probes to image and quantify bone growth and...
In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...
SDS, COAs, Manuals and more
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