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IVISense MMP 680 Fluorescent Probe (MMPSense)

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

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Save 10% on your first Revvity.com order. Use promo code below.
HELLO10
Feature Specification
Unit Size 1 vial (10 doses)
Specificity Matrix Metalloprotease

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

Click to copy promo code to clipboard.
Save 10% on your first Revvity.com order. Use promo code below.
HELLO10
Product Variants
Wave Length: 645 nm
Part #:
NEV10100
List Price
USD 706.60
Wave Length: 680 nm
Part #:
NEV10126
List Price
USD 702.04
Wave Length: 750 nm
Part #:
NEV10168
List Price
USD 702.04
For research use only. Not for use in diagnostic procedures.
USD 702.04
Your Price: Login to view

Overview

IVISense MMP 680 is excited by 680 + 10 nm excitation light, and emits at 700 + 10 nm. MMP 680 has an optimal imaging window of 24-36 hours after injection, allowing workflow flexibility in acquiring data in large animal cohorts. Including IVISense MMP 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

Specifications

Brand
IVISense
Fluorescent Agent Type
Enzyme activated
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Specificity
Matrix Metalloprotease
Storage Conditions
+2 to +8 °C
Therapeutic Area
Arthritis
Atherosclerosis
Bone loss
Cardiovascular
Inflammation
Oncology
Pulmonary
Vascular
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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1-6 of 9 Resources
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Flyer
Advancing inflammation, arthritis and oncology disease research with IVISense MMP probes
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Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Application Note
Multiplex 2D imaging of NIR molecular imaging agents on the IVIS SpectrumCT platform

Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...

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Application Note
Quantitative analysis of 3D microtissue growth and biomarker intensity

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