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IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)

IVISense™ Hypoxia CA IX 680 (HypoxiSense™ 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Wave Length 680 nm

IVISense™ Hypoxia CA IX 680 (HypoxiSense™ 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.

Product Variant
Unit Size: 1 Vial (10 doses)
Part #:
NEV11070
List Price
USD 572.84

Overview

In cancer, hypoxia occurs in tumors as a result of the poor ability of their disorganized vascular networks to deliver blood borne oxygen. IVISense Hypoxia CA IX 680 fluorescent imaging probe detects the tumor cell surface expression of carbonic anhydrase 9 (CA IX) protein, which increases in hypoxic regions within many tumors, especially in cervical, colorectal, non-small cell lung tumors. Pairing IVISense Hypoxia CA IX 680 agent with optical fluorescent imaging technology allows you to image and quantitate tumor sub-regions undergoing hypoxia-related changes, non-invasively and in vivo.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Therapeutic Area
Angiogenesis
Arthritis
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
680 nm

Resources

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1-6 of 6 Resources
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Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Application Note
Quantitative analysis of 3D microtissue growth and biomarker intensity
Protocol/SOP
Protocol/SOP
SOP: IVISense Hypoxia CA IX 680 (NEV11070) for in vivo imaging
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Whitepaper
Understanding the ‘how’ and ‘why’ of spectral unmixing

In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...

SDS, COAs, Manuals and more

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Safety data sheet
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Technical data sheet
  • Lot number
    ANY
    Lot date
    September 6, 2023
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