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IVISbrite 4T1 Red F-luc Bioluminescent Tumor Cell line (Bioware Brite)

The IVISbrite™ 4T1 Red F-luc tumor cell line (Bioware® Brite 4T1-Red-FLuc) is a light-producing cell line derived from 4T1 mouse mammary gland adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

For research use only. Not for use in diagnostic procedures.

The IVISbrite™ 4T1 Red F-luc tumor cell line (Bioware® Brite 4T1-Red-FLuc) is a light-producing cell line derived from 4T1 mouse mammary gland adenocarcinoma. The cells have been stably transduced with the red-shifted firefly luciferase gene from Luciola Italica (Red F-luc), for a brighter, red-shifted signal.

For research use only. Not for use in diagnostic procedures.

Overview

IVISbrite 4T1 Red F-luc Bioluminescent Tumor Cell line

  • Organism: Mouse
  • Tissue: Mammary Gland
  • Disease: Adenocarcinoma
  • Optical Reporter: Red F-luc

This cell line has very bright bioluminescence, emitting at least 15,000 photons/cell/sec in vitro. The exact number will vary depending on imaging and culturing conditions.

We recommend using this line in Nude and SCID mouse models. An immune response may occur in Balb/c mice.

By emitting intensified, longer wavelength light that is significantly brighter than other firefly luciferases, our bioluminescent oncology cell lines allow you to visualize and monitor the growth of deep tissue tumors in vivo.

After the cells are injected into an appropriate mouse model, the optimized Red F-luc luciferase enables more sensitive in vivo optical detection with less tissue attenuation so you can detect tumor development earlier, and monitor tumor growth and metastases in both subcutaneous and orthotopic models.

Specifications

Brand
IVISbrite
Cancer Model
Breast
Imaging Modality
Bioluminenscence
Luciferase Classification
Firefly
Shipping Conditions
Shipped in Dry Ice
Unit Size
2 vials each containing 1 million cells

Resources

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Application Note
Improved deep-tissue imaging with red-shifted luciferase tumor cell lines

The application note demonstrates how our IVISbrite tumor cell lines labeled with red-shifted luciferase (Red F-luc) yields a 100...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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FAQ
IVISbrite Tumor cell lines and substrates
Protocol/SOP
Protocol/SOP
SOP: IVISbrite tumor cell culture guidelines
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Flyer
The 5 most common mistakes to avoid when culturing IVISbrite tumor cells
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