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Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.

For research use only. Not for use in diagnostic procedures.

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Feature	Specification
µg protein/unit	10 µg protein / unit
Concentration	10 µg/µL protein
G-Alpha Natural Receptor	G_q/G₁₁
Host Cell Line	UC11
Host Species	Human
Receptor	Tachykinin
Target Class	GPCR
Validation	Binding
Volume	400.0 µL

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Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.

For research use only. Not for use in diagnostic procedures.

View product information

Product Variant

Unit Size: 400 units

Part #:

6110551400UA

List Price

USD 2,655.00

Product information

Overview

Membrane Target Systems are quality assured frozen membranes from cells that express Neurokinin NK1 (human) recombinant or endogenous receptors.

We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).

Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

Specifications

Physical Specifications

Concentration	10 µg/µL protein
Volume	400.0 µL
µg protein/unit	10 µg protein / unit

Other Specifications

Application	Drug Discovery & Development
Brand	Membrane Target Systems
Buffer/Solvent	50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
G-Alpha Natural Receptor	G_q/G₁₁
Host Cell Line	UC11
Host Species	Human
Product Group	Membrane Preparation
Receptor	Tachykinin
Shipping Conditions	Shipped in Dry Ice
Target Class	GPCR
Therapeutic Area	Cardiovascular Central Nervous System Gastrointestinal
Unit Size	400 units
Validation	Binding