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GSP Neonatal 17α-OH-progesterone kit

Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11α-hydroxylase deficiency.

Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.

Feature Specification
Application Newborn Screening

Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11α-hydroxylase deficiency.

Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.

Product Variant
Unit Size: 12 plates
Part #:
3305-0010
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Overview

These types represent 95% of CAH cases and in both, the 17α-OH progesterone (17OHP), a precursor of cortisol, is increased. The determination of 17OHP is thus a useful screening method for 95% of all CAH cases.

GSP Neonatal 17α-OH-progesterone assay

The GSP Neonatal 17α-OH-progesterone assay is intended for the quantitative determination of 17OHP in dried blood spot specimens as an aid in screening newborns for CAH.

  • Incubation time 3 h
  • Sensitive, robust DELFIA chemistry for confidence in results
  • Not affected by EDTA, citrate or heparin in samples
  • All reagents are ready to use
  • Contains reagents and plates for 1152 tests (12 plates)

Specifications

Application
Newborn Screening
Brand
GSP®
Detection Modality
Time-Resolved Fluorescence (TRF)
Disorders
Congenital Adrenal Hyperplasia (CAH)
Instrument Compatibility
GSP
Quantity
1152 tests
Sample Type
Dried blood spots
Technology
DELFIA
Unit Size
12 plates

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