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Glucagon, Receptor Grade, [125I]-, 50µCi

Glucagon, labeled with 125I. This product is receptor grade, and was developed for use in receptor binding assays. Glucagon binds and activates glucagon receptor, a GPCR that is a potential drug target for diabetes, hyperplasia, and pancreatic disorders.

For research use only. Not for use in diagnostic procedures.

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SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Molecular Weight 3608
Receptor Glucagon

Glucagon, labeled with 125I. This product is receptor grade, and was developed for use in receptor binding assays. Glucagon binds and activates glucagon receptor, a GPCR that is a potential drug target for diabetes, hyperplasia, and pancreatic disorders.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Unit Size: 10 µCi
Part #:
NEX207010UC
List Price
USD 1,848.00
Unit Size: 50 µCi
Part #:
NEX207050UC
List Price
USD 3,903.00

Overview

50 µCi Quantities of Glucagon, Receptor Grade, [125I]-, are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX207:

  1. Bizeau, M.E. & Hazel, J.R., (2000), Membrane physical properties do not explain increased cyclic AMP production in hepatocytes from rats fed menhaden oil, Lipids, 35: 595-600.
  2. Lee, C., Hamm, M.W., (1989), Effect of Dietary Fat and Cholesterol Supplements on Glucagon Receptor Binding and Adenylate Cyclase Activity of Rat Liver Plasma Membrane, The Journal of Nutrition, 119 (4): 539–546.

Specifications

Molecular Weight
3608
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
0.08M Tris HCl, 0.08M NaCl, 0.05M ßmercaptoethanol, 0.25% BSA, 50 KIU/ml Trasylol®, (pH 8.5): n-propanol, 1:1
Detection Modality
Radiometric
Fresh Lot Days
First Monday of each month
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Glucagon
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
4°C
Therapeutic Area
Diabetes
Unit Size
50 µCi

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