Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
For research use only. Not for use in diagnostic procedures
Flunitrazepam acts as an agonist at GABAA receptors. This receptor is an aionotropic receptor and ligand-gated ion channel. Flunitrazepam is used to treat severe insomnia and has also been used as an anesthetic.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET567:
Molecular Weight |
313.3
|
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Application |
Drug Discovery & Development
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Brand |
NEN Radiochemicals
|
Detection Method |
Radiometric
|
Label Position |
Specifically Labeled
|
One Unit Contains |
250.0 µCi
|
Radionuclide |
3H
|
Radioisotope |
H-3
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Receptor Type |
Benzodiazepine
GABAA
|
Shipping Conditions |
Shipped Ambient
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Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Therapeutic Area |
CNS & Neurologic
|
Unit Size |
250 µCi
|
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