DTG (Ditolylguanidine), tritiated on the p-ring and at the 5- position. DTG is a selective sigma receptor (σ-receptor) agonist.
For research use only. Not for use in diagnostic procedures
Ditolylguanidine acts as an agonist at sigma receptors (σ1 and σ2), and has neuroprotective and antidepressant effects.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET986:
Molecular Weight |
239.32
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Application |
Drug Discovery & Development
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Brand |
NEN Radiochemicals
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Detection Method |
Radiometric
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Label Position |
Nominally Labeled
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One Unit Contains |
250.0 µCi
|
Radionuclide |
3H
|
Radioisotope |
H-3
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Shipping Conditions |
Shipped in Dry Ice
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Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
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Therapeutic Area |
Cancer
CNS & Neurologic
|
Unit Size |
250 µCi
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