CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.
For research use only. Not for use in diagnostic procedures
250 µCi quantity of CP 55940, [Side Chain-2,3,4-3H(N)]-, is available for your research.
CP 55,940 is a synthetic cannabinoid that mimics the effects of naturally occuring tetrahydrocannabinol (THC). It acts as a full agonist at cannabinoid receptors type 1 and 2. These GPCRs are potential drug targets for a variety of diseases, including epilepsy, cancer, obesity, and osteoporosis.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET1051:
Molecular Weight |
376
|
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Application |
Drug Discovery & Development
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Brand |
NEN Radiochemicals
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Detection Method |
Radiometric
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Label Position |
Nominally Labeled
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One Unit Contains |
250.0 µCi
|
Radionuclide |
3H
|
Radioisotope |
H-3
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Receptor Type |
Cannabinoid
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Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
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Therapeutic Area |
Angiogenesis
Cardiovascular
CNS & Neurologic
Gastrointestinal
Inflammation
Metabolic Disorders
Pain
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Unit Size |
250 µCi
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