Our ViewPlate microplates are engineered for bottom reading systems and high content imaging. Glass exhibits better optical properties and is perfectly flat, but is less-suited for cell culture. Glass therefore usually has to be coated with proteins that enhance cell adherence and growth (e.g., poly-D-lysine or collagen). This high quality microplate can be utilized in your cell based assay for superior results.

Extracellular matrix proteins such as collagen provide an attachment framework for the adhesion and growth of certain cell types in vivo, and can also be used for cell attachment to plate surfaces in vitro. Cellular fibronectin membrane proteins mediate the attachment of cells to collagen substrates. Collagen is the most abundant protein in mammals that is found throughout the body and is a major component of the extracellular matrix (ECM). The most frequently used types of collagen for coating are collagen I and IV. Collagen type I is suitable for endothelial and epithelial cells, muscle cells and hepatocytes. Collagen type IV is the major constituent of basement membranes and offers more physiologically relevant conditions to cells as well as improving the adherence of specific cell types i.e. PC-12 (rat adrenal pheochromocytoma cell line). Our catalog plates are coated with rat tail collagen Type I.

Leveraging years of assay and instrument experience in plate detection, Revvity designs better microplates for better performance that guarantees better results for all Revvity applications.