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Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)
Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)
Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.
For research use only. Not for use in diagnostic procedures.
| Feature | Specification |
|---|---|
| Concentration | 0.05 mCi/mL |
| Label Position | Specifically Labeled |
| Molecular Weight | 192.12 |
Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.
For research use only. Not for use in diagnostic procedures.
Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)
Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)
Product information
Overview
ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.
Specifications
| Concentration |
0.05 mCi/mL
|
|---|---|
| Molecular Weight |
192.12
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
NEN Radiochemicals
|
| Buffer/Solvent |
Ethanol : water (2:98)
|
| Detection Modality |
Radiometric
|
| Label Position |
Specifically Labeled
|
| Packaging |
NENSure vial
|
| Radioisotope |
14C
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
| Storage Conditions |
5°C
|
| Unit Size |
50 µCi
|
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