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Chromium-51 Radionuclide, 2mCi (74MBq), Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Concentration 1 mCi/mL
Fresh Lot Days Every other Friday

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

For research use only. Not for use in diagnostic procedures.

Product Variants
Unit Size: 1 mCi
Part #:
NEZ030S001MC
List Price
USD 658.30
Unit Size: 2 mCi
Part #:
NEZ030S002MC
List Price
USD 781.39
Unit Size: 5 mCi
Part #:
NEZ030S005MC
List Price
USD 1,349.00
Unit Size: 10 mCi
Part #:
NEZ030S010MC
List Price
USD 2,506.00

Overview

2 mCi Quantities of Chromium-51 Radionuclide, Sodium Chromate in Normal Saline (pH 8-10), Steri-packaged are available for your research.

Chromium-51 is the most commonly used readioactive marker for the labeling of target cells in cytotoxicity assays. The common name for such assays Chromium Release also describes the fundamental method behind the assay procedure. Methods for the precise and accurate quantification of cytotoxicity are of fundamental importance in immunology particularly for the study of tumor and virus cytolysis.

Cytotoxicity assays can be used in order to study either the defense mechanism in a specific patient or to study target cells, depending on whether the effector (or killer) cells are the unknowns. It can also be used for the study of certain drugs on the immune system.

Chromium fulfills the requirement of a good label. It is generally non-toxic (as Na2CrO4), it is easily taken up by the cells, it is spontaneously released only in relatively small amounts, its detection is easy and sensitive and it does not change the morphology and characteristics of the target cell.

Specifications

Concentration
1 mCi/mL
Brand
NEN Radiochemicals
Buffer/Solvent
Saline
Detection Modality
Radiometric
Fresh Lot Days
Every other Friday
Label Position
Specifically Labeled
Radioisotope
51Cr
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
Room temperature
Unit Size
2 mCi

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