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Chromium-51 Radionuclide, 1mCi (37MBq), Sodium Chromate in Normal Saline (pH 8-10)

Chromium-51 (51Cr) radionuclide, commonly used as a label for target cells in chromium release assays, cell-mediated cytotoxicity studies, antibody-dependent cytotoxicity (ADCC) studies, and CAR-T cell development. Target cells uptake 51Cr radionuclide, and release the nuclide into the culture media upon cytolysis or cell death.

For research use only. Not for use in diagnostic procedures

Product Variants
Part number: NEZ030001MC
Unit Size: 1 mCi
List price: USD 662.70
Your price:
USD 662.70
USD 662.70 /each
Part number: NEZ030002MC
Unit Size: 2 mCi
List price: USD 789.08
Your price:
USD 0.00
USD 789.08 /each
Part number: NEZ030005MC
Unit Size: 5 mCi
List price: USD 1,372.00
Your price:
USD 0.00
USD 1,372.00 /each
Part number: NEZ030010MC
Unit Size: 10 mCi
List price: USD 2,533.00
Your price:
USD 0.00
USD 2,533.00 /each

Overview

1 mCi Quantities of Chromium-51 Radionuclide, Sodium Chromate in Normal Saline (pH 8-10) are available for your research.

Chromium-51 is the most commonly used readioactive marker for the labeling of target cells in cytotoxicity assays. The common name for such assays Chromium Release also describes the fundamental method behind the assay procedure. Methods for the precise and accurate quantification of cytotoxicity are of fundamental importance in immunology particularly for the study of tumor and virus cytolysis.

Cytotoxicity assays can be used in order to study either the defense mechanism in a specific patient or to study target cells, depending on whether the effector (or killer) cells are the unknowns. It can also be used for the study of certain drugs on the immune system.

Chromium fulfills the requirement of a good label. It is generally non-toxic (as Na2CrO4), it is easily taken up by the cells, it is spontaneously released only in relatively small amounts, its detection is easy and sensitive and it does not change the morphology and characteristics of the target cell.

Specifications

Concentration
5 mCi/mL
Brand
NEN Radiochemicals
Detection Method
Radiometric
Fresh Lot Days
Every other Friday
Label Position
Specifically Labeled
Radionuclide
51Cr
Radioisotope
Cr-51
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size
1 mCi

Resources

1-1 of 1 Resources
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Guide
Chromium-51 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Chromium-51. While we...

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