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CGP 42112A, [125I]-, 25µCi

CGP 42112A, labeled with 125I. CGP 42112A acts as an agonist at angiotensin AT2 receptors.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Fresh Lot Days Third Monday of even months
Label Position Nominally Labeled
Molecular Weight 1176
Receptor Angiotensin

CGP 42112A, labeled with 125I. CGP 42112A acts as an agonist at angiotensin AT2 receptors.

For research use only. Not for use in diagnostic procedures.

Product Variants
Unit Size: 5 µCi
Part #:
NEX324005UC
List Price
USD 1,335.00
Unit Size: 25 µCi
Part #:
NEX324025UC
List Price
USD 4,912.00

Overview

25 µCi Quantities of CGP 42112A, [125I]- are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX324:

  1. Chi, Y.H., Lee, J.H., Kim, J.H., Tan, H.K., Kim, S.L., Lee, J.Y., Rim, H.K., Paik, S.H., Lee, K.T. (2013), Pharmacological characterization of BR-A-657, a highly potent nonpeptide angiotensin II receptor antagonist. Biol Pharm Bull, 36 (7): 1208-1215.

Specifications

Molecular Weight
1176
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Lyophilized
Detection Modality
Radiometric
Fresh Lot Days
Third Monday of even months
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Angiotensin
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
4°C
Therapeutic Area
Angiogenesis
Cardiovascular
Unit Size
25 µCi

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