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N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
For research use only. Not for use in diagnostic procedures.
| Feature | Specification |
|---|---|
| Fresh Lot Days | Fresh upon request |
| Label Position | Nominally Labeled |
| Molecular Weight | 387.2 |
Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.
For research use only. Not for use in diagnostic procedures.
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
Product information
Overview
Iodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues. Available in 250 µCi size.
Specifications
| Molecular Weight |
387.2
|
|---|---|
| Specific Activity |
2200.0 Ci/mmol
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
NEN Radiochemicals
|
| Buffer/Solvent |
Anhydrous 2-methyltetrahydrofuran with 250 ppm BHT (butylated hydroxytoluene) stabilizer
|
| Detection Modality |
Radiometric
|
| Fresh Lot Days |
Fresh upon request
|
| Label Position |
Nominally Labeled
|
| Packaging |
NENSure vial
|
| Radioisotope |
125I
|
| Shipping Conditions |
Shipped Ambient
|
| Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
| Storage Conditions |
Ambient or lower
|
| Unit Size |
250 µCi
|
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