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Apelin 13 [125I], 50 µCi

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Fresh Lot Days Fresh upon request
Label Position Nominally Labeled
Molecular Weight 1654.75
Receptor Apelin

Apelin, labeled with 125 I. Apelin is the endogenous ligand for apelin receptors, and is used in receptor binding studies. Apelin 13 is a 13-amino acid peptide corresponding to residues 65-77.

For research use only. Not for use in diagnostic procedures.

Product Variants
Unit Size: 10 µCi
Part #:
NEX393010UC
List Price
USD 1,792.00
Unit Size: 25 µCi
Part #:
NEX393025UC
List Price
USD 3,203.00
Unit Size: 50 µCi
Part #:
NEX393050UC
List Price
USD 5,715.00

Overview

50 µCi Quantities of Apelin 13 [125I] are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX393:

  1. Ma, Y. et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure 25, 858–866.e4 (2017).

Specifications

Molecular Weight
1654.75
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
50mM sodium acetate at pH 4 containing 5% sucrose and 0.25% BSA
Detection Modality
Radiometric
Fresh Lot Days
Fresh upon request
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Apelin
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
4°C
Therapeutic Area
Cardiovascular
CNS & Neurologic
Gastrointestinal
Unit Size
50 µCi

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