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AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
The AlphaLISA™ Human RIG-I Binding Kit is designed to select and characterize compounds that specifically bind human RIG-I protein.
| Feature | Specification |
|---|---|
| Application | Protein Quantification |
| Sample Volume | 5 µL |
The AlphaLISA™ Human RIG-I Binding Kit is designed to select and characterize compounds that specifically bind human RIG-I protein.
AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
Product information
Overview
RIG-I (Retinoic acid-Inducible Gene I) is a cytosolic pattern recognition receptor which is known to recognize RNA pathogens in cells. This protein triggers a type 1 interferon response and participates in the innate immune system. By identifying viral dsRNA, the RIG-I protein recognizes infected cells. The N-terminus of RIG-I contacts mitochondrial antiviral signaling proteins after being triggered by a dsRNA, thereby triggering the IFN-1 signaling pathway. Recent studies have shown that RIG-I is also involved in cancer, lupus nephritis, immunoglobulin A nephropathy, Crohn’s disease, and atherosclerosis.
Formats
- Our 500 assay point kit allows you to run 500 wells in a 384-well format, using a 20 µL reaction volume (5 µL of sample).
- Our 5,000 assay point kit allows you to run 5,000 wells in a 384-well format, using a 20 µL reaction volume (5 µL of sample).
Features
- No-wash steps, no separation steps
- ELISA alternative technology
- Sensitive detection
- Small sample volume
Specifications
| Application |
Protein Quantification
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
AlphaLISA
|
| Detection Modality |
Alpha
|
| Product Group |
Kit
|
| Sample Volume |
5 µL
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Target |
RIG-I
|
| Target Class |
Biomarkers
|
| Technology |
Alpha
|
| Therapeutic Area |
Autoimmunity
|
| Unit Size |
500 assay points
|
Video gallery
AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
AlphaLISA Human RIG-1 Binding Kit, 500 Assay Points
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