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AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
The AlphaLISA™ SureFire® Ultra™ Human Total TREM2/DAP12 Complex assay is a sandwich immunoassay for quantitative detection of total TREM2/DAP12 Complex in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Protein-Protein Interaction |
| Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human Total TREM2/DAP12 Complex assay is a sandwich immunoassay for quantitative detection of total TREM2/DAP12 Complex in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
Product information
Overview
The TREM-2 (Triggering Receptor Expressed on Myeloid Cells 2) family of receptors regulates the immune system's various cell types, such as neutrophils, monocyte/macrophages, microglia, and dendritic cells. TREM-2 requires the adaptor protein DAP12 for downstream signaling. Human cerebrospinal fluid (CSF) has been shown to include soluble TREM-2, which has been reported to be increased in people with multiple sclerosis and other inflammatory neurological illnesses compared to those without such conditions.
The AlphaLISA SureFire Human Total TREM2/DAP12 Complex is a sandwich immunoassay for the quantitative detection of total TREM2/DAP12 complex in cellular lysates, using Alpha Technology.
Formats:
- The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
- The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
- The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
- The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
- Cell and tissue lysates
- Antibody modulators
- Biotherapeutic antibodies
Alpha SureFire kits can be used for:
- Cellular kinase assays
- Receptor activation studies
- Screening
Specifications
| Application |
Protein-Protein Interaction
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
AlphaLISA SureFire Ultra
|
| Detection Modality |
Alpha
|
| Lysis Buffer Compatibility |
Lysis Buffer
|
| Product Group |
Kit
|
| Sample Volume |
10 µL
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Target |
TREM2/DAP12
|
| Target Class |
Binding Assay
|
| Target Species |
Human
|
| Technology |
Alpha
|
| Therapeutic Area |
Neuroscience
|
| Unit Size |
500 Assay Points
|
Video gallery
AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
AlphaLISA SureFire Ultra Human binding TREM2 / DAP12 Detection Kit, 500 Assay Points
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