The AlphaLISA™ SureFire® Ultra™ Human Total TREM2/DAP12 Complex assay is a sandwich immunoassay for quantitative detection of total TREM2/DAP12 Complex in cellular lysates using Alpha Technology.
The TREM-2 (Triggering Receptor Expressed on Myeloid Cells 2) family of receptors regulates the immune system's various cell types, such as neutrophils, monocyte/macrophages, microglia, and dendritic cells. TREM-2 requires the adaptor protein DAP12 for downstream signaling. Human cerebrospinal fluid (CSF) has been shown to include soluble TREM-2, which has been reported to be increased in people with multiple sclerosis and other inflammatory neurological illnesses compared to those without such conditions.
The AlphaLISA SureFire Human Total TREM2/DAP12 Complex is a sandwich immunoassay for the quantitative detection of total TREM2/DAP12 complex in cellular lysates, using Alpha Technology.
For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Application |
Protein Detection
|
---|---|
Assay Target |
TREM2/DAP12
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Neuroscience
|
Unit Size |
10,000 Assay Points
|
This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...
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