The AlphaLISA™ SureFire® Ultra™ Human Phospho-TDP-43 (Ser409/410) assay is a sandwich immunoassay for quantitative detection of phospho-TDP-43 (Ser409/410) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
TAR DNA binding protein 43 (TDP-43) is a nucleic acid binding protein involved in RNA-related metabolism. In pathological conditions (mutation or deregulation), TDP-43 forms insoluble inclusion bodies in the cytoplasm of neurons in the brain and spinal cord. Aggregated TDP-43 has been identified as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD), and more widely in several neurodegenerative diseases such as Alzheimer’s disease.
The AlphaLISA SureFire Ultra Human Phospho-TDP-43 (Ser409/410) is a sandwich immunoassay for the quantitative detection of phospho-TDP-43 (Ser409/410) in cellular lysates, using Alpha Technology.
Application |
Protein Detection
|
---|---|
Assay Points |
50000
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Experimental Type |
In vitro
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
|
Therapeutic Area |
Neuroscience
|
Unit Size |
50,000 Assay Points
|
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