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AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
The AlphaLISA™ SureFire® Ultra™ Human Phospho-Tau (Ser214) assay is a sandwich immunoassay for quantitative detection of phospho-Tau (Ser214) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Cell Signaling |
| Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human Phospho-Tau (Ser214) assay is a sandwich immunoassay for quantitative detection of phospho-Tau (Ser214) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
Product information
Overview
Tau, also known as MAPT (Microtubule Associated Protein Tau), is a phosphoprotein that is mostly produced in neurons of the central nervous system and is involved in microtubule construction and stability. Around 85 phosphorylation sites are present in Tau, and numerous kinases, including CDK5, MAP kinase, and GSK3 (Tau's primary kinase), can phosphorylate these sites. Numerous neurodegenerative diseases, including Tauopathy, Parkinson's, and Alzheimer's, are characterized by Tau hyperphosphorylation and aggregation.
The AlphaLISA SureFire Human Phospho-Tau (Ser214) Detection Kit is a sandwich immunoassay for the quantitative detection of phosphorylated tau Ser214 in cellular lysates, using Alpha Technology.
Formats
- The HV (high volume) Tau kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
- The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
- The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
- The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with
- Cell and tissue lysates
- Antibody modulators
- Biotherapeutic antibodies
Alpha SureFire kits can be used for
- Cellular kinase assays
- Receptor activation studies
- Screening
Specifications
| Application |
Cell Signaling
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
AlphaLISA SureFire Ultra
|
| Detection Modality |
Alpha
|
| Lysis Buffer Compatibility |
Lysis Buffer
|
| Molecular Modification |
Phosphorylation
|
| Product Group |
Kit
|
| Sample Volume |
10 µL
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Target |
Tau
|
| Target Class |
Phosphoproteins
|
| Target Species |
Human
|
| Technology |
Alpha
|
| Therapeutic Area |
Neuroscience
|
| Unit Size |
10,000 Assay Points
|
Video gallery
AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Human Phospho-Tau (Ser214) Detection Kit, 10,000 Assay Points
Resources
Are you looking for resources, click on the resource type to explore further.
Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...
The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies...
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